Destiny 2: 5 Best Weapons for PvE

Confused about which weapons best suit your Guardian? Check out our breakdown of the 5 best weapons for the PvE game mode in Destiny 2.

5 Best Weapons for PvE in Destiny 2 (Image via Bungie)
5 Best Weapons for PvE in Destiny 2 (Image via Bungie)

Destiny 2 dominates the looter-shooter genre with its ever-changing sandbox, rewarding combat, and deep skill tree system. Whether you’re prepping for raids, dungeons, or high-tier boss arenas, having the right arsenal can make or break your situation. With frequent updates, balance patches, and new weapons, the meta is always shifting, especially in PvE. Bungie has introduced new perks, reworked archetypes, and even brought back some fan-favorite weapons.

Destiny 2’s PvE meta offers a mix of exotic and legendary weapons. This ensures a perfect weapon for every playstyle in the game. You can choose from an arsenal of weapons that can melt a boss’s health in seconds to effortless crowd controllers. The best weapons will maximize your DPS output and efficiency.

This guide covers the top 5 best PvE weapons in Destiny 2 right now. These top 5 picks will elevate your Guardian’s lethality in the game mode.

Top 5 Weapons for PvE in Destiny 2

Buried Bloodline

Buried Bloodline
A crossbow that fires two shots – Buried Bloodline (Image via Bungie)

Although classified as a sidearm, Buried Bloodline is a crossbow weapon that remains consistently dominant. It fires twice simultaneously, and if both shots hit the target, you trigger lifesteal from them. Moreover, the shots fired from this weapon are completely homing and track their target.

This weapon enhances stats and provides additional perks once upgraded to a Masterwork. Upon getting a multikill, you gain Devour stacks, which weaken your enemies. Non-void subclass builds can make better use of Buried Bloodline due to this.

Third Iteration

Grants invisibility and true sight - Third Iteration (Image via Bungie)
Grants invisibility and true sight – Third Iteration (Image via Bungie)

An exotic scout rifle, Third Iteration is a weapon that fires a spread of void energy projectiles. This spread can be compressed into a high-density singular projectile while aiming down sights that marks the target. Marked targets then receive more damage from the Third Iteration. Additionally, killing a marked target or landing a precision final blow on them grants invisibility and true sight for a while. This can be very useful for sniping enemies from afar while staying stealthy in PvE scenarios.

Wicked Implement

A must-have for PvE battles - Wicked Implement (Image via Bungie)
A must-have for PvE battles – Wicked Implement (Image via Bungie)

Wicked Implement is another exotic scout rifle that fires Stasis rounds. This weapon is capable of applying slow to the target when hit with precision shots in rapid succession. Wicked Implement’s Tithing Harvest perk also refills the magazine when collecting Stasis Shards.

These shards can be collected by destroying Stasis Crystals or by getting precision hits. This auto-reloads your weapon mid-fight and continues your onslaught in battle. Wicked Implement is a must for PvE game modes, as it can freeze groups of enemies in their tracks.

New Land Beyond

Deal heavy damage from afar with New Land Beyond (Image via Bungie)
Deal heavy damage from afar with New Land Beyond (Image via Bungie)

An exotic sniper rifle that increases weapon damage every time it lands a precision hit, New Land Beyond is capable of dealing heavy damage from far distances. It can dish out an ungodly amount of damage to a single target before it knows what hit it. New Land Beyond fires kinetic rounds that also increase the weapon’s reload speed, handling, and target acquisition. This makes it a perfect weapon for tankier enemies in PvE.

Legend of Acrius

A weapon from vanilla Destiny 1 (Image via Bungie)
A weapon from vanilla Destiny 1 (Image via Bungie)

A weapon from vanilla Destiny 1 that fires high-damage Arc energy bullets, Legend of Acrius is an exotic shotgun that packs a punch and still hits like a truck. This weapon’s intrinsic trait, called Shock Blast, allows it to overpenetrate enemies. The Trench Barrel perk also increases the damage of the next three rounds after a melee attack. This helps players stay in the enemy’s face while alternating between melee and shotgun attacks.


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