Discover everything you need to know about the Gamma Gun Ghoul build in Fallout 76, including the best perk cards and weapons.

Ghouls in Fallout 76 are humans who have survived a nuclear holocaust, and they exhibit a zombie-like appearance. They are resistant to radiation damage and have enhanced regeneration. With the arrival of a recent update, Ghoul received 28 new Perk cards and 2 legendary Perk cards. The Gamma Gun Ghoul Build in Fallout 76 is a unique build that focuses on using the Gamma Gun while taking full advantage of the Ghoul mutation.
This build is particularly effective for solo players who want to tank damage and deal radiation damage. Choosing the best perk cards is essential in the game, as your gameplay mostly depends on it. Concentrated Fire is one of the best perks for a Gamma Gun Ghoul build because it increases the damage done to a specific body part in VATS each time. In this guide, we’ll discuss the best Gamma Gun Ghoul build in Fallout 76, including some useful tips and tricks and the best perks to use.
Everything About Gamma Gun Ghoul Build in Fallout 76
The Gamma Gun Ghoul Build in Fallout 76 is a unique setup in Fallout 76 as it offers a combination of radiation damage and the Ghoul mutation. Our build includes Gamma Gun as a primary damage-dealing weapon and Gatling Plasma as a backup weapon. T-65 Power Armor is the best armor to equip because it provides maximum protection to your character in combat. Use the perks like Concentrated Fire, Gunslinger, Heavy Gunner, Radioactive Strength, and Ghoulish. These are the best perks to include for the Gamma Gun Ghoul build. Focus on Attributes like Strength, Perception, and Endurance to improve your damage output. Perception is crucial for hitting targets with the Gamma Gun, especially in crowd control situations. Endurance helps with overall health and boosts your radiation resistance. Make sure you have enough supply of grenades in your inventory to eliminate a cluster of enemies.
Gamma Gun Build Pros | Gamma Gun Build Cons |
---|---|
Radiation Damage | Limited Range |
Durability | Gamma Gun Ammo |
Radiation Healing |
Best Strategy For Gamma Gun Ghoul Build in Fallout 76
The Gamma Gun Ghoul Build in Fallout 76 is all about maximizing your radiation damage output. Ghouls are resistant to radiation damage and have increased damage output from it. Use the Gamma Gun to deal radiation damage, allowing you to dominate enemies. you can use Gatling Plasma as your secondary weapon to deal damage if you notice your primary weapon isn’t working properly. Use the perk that complements your playstyle and build as well. T-65 Power Armor is the best choice to equip as it increases your survivability by reducing the effectiveness of incoming attacks.
Use Radstorms to maximize your health regeneration while you deal damage with your primary weapon. Make sure you have Chems and food supply in your inventory to instant buffs to your Gamma Gun Ghoul build. Keep a distance from the enemy to deal massive radiation damage in combat. Guerrilla Master is one of the best perk cards to unlock because it allows you to have +5% ranged damage to close enemies per Outslaught stack and +5% max stacks. Use First Aid to heal with your Stimpaks, allowing you to increase your survivability in the game as well.
Best Weapons For Gamma Gun Ghoul Build in Fallout 76

Here are the best weapons for the Gamma Gun Ghoul build in Fallout 76.
Gamma Gun
- Damage: 60
- Level: 45
- Radiation Damage: 50
- Ammo Gamma Round
- Magazine Size: 8
- Fire rate 67
- Range: 120
- AP Cost: 30
The Gamma Gun is a powerful weapon that deals radiation damage, making it a perfect choice for a Gamma Gun Ghoul build. This weapon helps maintain desired radiation levels. You’re immune to radiation as a Ghoul, so you can’t take radiation damage. The Quad legendary effect significantly enhances the Gamma Gun’s utility. This allows it to fire multiple shots per magazine. It enhances its damage output and effectiveness in combat. The Gamma Gun’s projectiles are difficult to dodge. This also makes it a perfect choice for PVP combat. The Gamma Gun’s radiation-penetrating damage allows you to deal damage to enemies who are immune to radiation. Other legendary effects like Two Shot or Bloodied are also effective on the Gamma Gun. This is the best weapon to choose if you want to run a Gamma Gun Ghoul build in Fallout 76.
Gatling Plasma
- Fire Rate: 114
- Range: 204
- Ap Cost: 10
- Capacity: 500
- Accuracy: 53
- Weight: 2.7
Gatling Plasma is the best weapon for the Gamma Sun Ghoul build in Fallout 76. Use this weapon as a backup when your Gamma Gun isn’t bringing any positive outcomes. This is a heavy weapon and fires very rapidly. This weapon uses Plasma cores rather than individual bullets. You can find this heavy weapon in higher-level areas of the map. You can purchase it from the MODUS armory terminal in the Whitespring bunker armory. The other way to get this weapon is to get it randomly in government aid drops at higher levels. This weapon comes with a large magazine capacity, allowing for extended combat without reloading. You can use it against various enemies, including those with armor.
Best Amour For Gamma Gun Ghoul Build in Fallout 76

Here is the best armor for the Gamma Gun Ghoul build in Fallout 76.
T-65 Power Armor
- Damage Resistance: 400
- Energy Resistance: 370
- Radiation Resistance: 415
T-60 Power Armor is the best choice to gain maximum protection and it can also boost your damage resistance. Use this armor to gain a massive boost in survivability and armor protection. T-65 is a solid option because the Gamma Gun builds rely on staying alive and eliminating enemies. This is perfect for tanking damage in close combat, especially with the Onslaught perk card. It provides good radiation protection, stronger than the T-45, T-51, and Ultracite. Use it with effective mods to make this armor even more powerful, increasing your survivability in the game. T-60 excels at protecting against radiation damage, making it a valuable choice in irradiated areas. T-60 is easier to find and acquire, making it a good choice for players who are still leveling up. It provides a good level of protection against ballistic damage. The chest piece can be further modified with various upgrades.
Hazmat Suit
- Radiation Resistance: 1000
- Value: 85
- Weight: 5
The Hazmat suit is an alternative to T-65 Power Armor as it prevents. Damage and disease from airborne and waterborne hazards. It also provides radiation resistance and helps you survive in environments with heavy radiation. This is a good option to utilize, as it offers decent damage resistance as well. If you haven’t found the T-65 Power Armor, then this is the best option to utilize in the early game.
Best Perks Gamma Gun Ghoul Build in Fallout 76
Radiation Power is the best perk to unlock for the Gamma Gun Ghoul build because it allows you to deal additional bonus damage to targets. Choose the perks that increase your survivability and boost your damage output with Gamma Gun. It allows you to take the benefits of your Ghoul’s abilities like radiation resistance.
- Adrenaline- Gain +10% (max 60%) damage for 30s per kill. Duration refreshes with kills.
- Ghoulish- Radiation now regenerates even more of your lost Health.
- Pack Rat- The weight of all junk items is reduced by 75%.
- Gunslinger Expert- +1% ranged weak spot damage per Onslaught stack, +3 max stacks.
- Rejuvenated- Benefits of being well-fed or Hydrated are further increased when you have less than 10% RADS.
- Radiation Power- Expend a small amount of Glow per hit to deal 20% bonus damage to targets.
Best Perks Beginner Build in Fallout 76
Gunslinger is the best perk for the beginner build in Fallout 76 because it allows your ranged weapons to deal massive damage. Choosing the right perk for the beginner Gamma Gun Ghoul build in Fallout 76 allows you to increase your character’s abilities and survivability. Here are some of the best perks to consider for your beginner build.
- Ironclad- Armor provides 25% more protection. Double if wearing a matching set.
- Gunslinger- Your ranged weapons do +12% weak spot damage.
- Scrapper- Obtain more components when you scrap weapons and armor.
- Lone Wanderer- Gain Resistances and AP Regen based on your CHA while not on a team.
- Spiritual Healer- Regenerate HP while on a team based on your CHA.
- Rad Specialist- Increase Rad intake by 25% on Armor & Power Armor, Double if wearing a matching set.
Best Main Stats Perks for Gamma Gun Ghoul Build in Fallout 76

Concentrated Fire is the best main stat perk for a Gamma Gun Ghoul build because it increases damage to specific body parts in VATS. You can allocate a total of 56 SPECIAL points to increase your character’s stats. You start with 1 point in each of the 7 SPECIAL attributes for a total of 7 points. And you gain 1 SPECIAL point every time you level up. You’ll have a total of 56 SPECIAL points to spend at level 50. Here are some of the best maintenance perks for the Gamma Gun Ghoul build in Fallout 76.
- First Aid- Stimpaks restore more HP based on your INT.
- Lone Wanderer- Gain Resistances and AP Regen based on your CHA while not on a team.
- Ghoulish- Reduces radiation damage you take and increases your natural resistance.
- Concentrated Fire- Focus fire to gain high accuracy and +3% damage per shot.
- Bloody Mess- This perk allows you to increase overall damage by 15% and provides an opportunity for foes to explode on death.
- Grim Reaper’s Sprint- Any kill in V.A.T.S. has a 35% chance to restore all Action Points.
Best Skill Perks for Gamma Gun Ghoul Build in Fallout 76
Heavy Gunner is the best skill perk for a Gamma Gun Ghoul build because it allows you to deal massive damage in tough encounters. The more damage your Gamma Gun deals, the more you can eliminate the enemies. Here are some of the best skill perks to consider for the Gamma Gun Ghoul build in Fallout 76.
- Concentrated Fire- V.A.T.S. targets limbs. Focus fire to gain more accuracy and damage per shot.
- Heavy Gunner- You gain additional damage to all heavy weapons.
- Pack Rat- The weight of all junk items is reduced by 75%.
- Feral Presence- Reduce your target’s damage output by 15% after you attack for 5 seconds.
- Jaguar Speed- Allows you to sprint faster when your Glow is high.
- Bone Shatterer- It provides a chance to cripple enemies, allowing you to decrease their mobility.
Best Combat Perks for Gamma Gun Ghoul Build in Fallout 76
Radioactive Strength is the best combat perk to use because it allows you to increase melee damage, enhancing your effectiveness in combat. These perks must synergize with the unique abilities and mechanics of the Gamma Gun Ghoul build. Here are some of the best combat-focused perks for the Gamma Gun Ghoul build.
- Radioactive Strength- It increases melee damage by 150%, significantly enhancing close-quarters combat effectiveness.
- Concentrated Fire- This allows you to target specific enemy body parts in V.A.T.S., enhancing your accuracy and damage with each shot.
- Heavy Gunner- Boost your damage potential with Heavy Weapons.
- Adrenaline- Gain additional damage for 30s per kill. Duration refreshes with kills.
- Serendipity- Gain a chance to avoid damage while below 35% health.
- Last Laugh- You drop a live grenade from your inventory when you die.
Best Potions For Gamma Gun Ghoul Build in Fallout 76
Here are the best potions for Gamma Gun Ghoul build in Fallout 76.
- Orange Mentats- +10% V.A.T.S. accuracy.
- Toxic Goo- Deals a high amount of radiation damage (125 rads) to the player but also provides a significant health restoration effect.
- Cranberry moonshine- This potion allows you to gain +1 Charisma, +1 Strength, -1 Intelligence, and HP max +25.
Best Tips and Tricks for Gamma Gun Ghoul Build in Fallout 76
Here are the best tips and tricks Gamma Gun Ghoul build in Fallout 76.
- While fighting enemies in close range, switch to melee weapons like Gatling Plasma.
- Use the perks that complement your playstyle and your Gamma Gun Ghoul build.
- Use the Radical Resistance perk to reduce the radiation damage.
- Use the high ground and covers to deal damage in tough encounters.
- Radical Resistance is a good perk to use because it reduces radiation damage.
- Use T-65 Power Armor to increase your survivability by mitigating the incoming damage.
- It’s best to use Gamma Gun for crowd control, so try to hit clusters of enemies to maximize the effectiveness of your weapon.
- Use the perk that increase the effectiveness like performance and damage output of your Gamma Gun in combat.
- You can increase the damage, accuracy, and range of the Gamma Gun with the right mod.
FAQs about Gamma Gun Ghoul build in Fallout 76
What is Ghoul in Fallout 76?
Ghouls in Fallout 76 are humans that are mutated by the radiation of the nuclear wasteland. Becoming a ghoul is a permanent change unless you manually revert.
What are the best combat perks for the Gamma Gun Ghoul build in Fallout 76?
Concentrated Fire, Gunslinger, Heavy Gunner, Radioactive Strength, and Ghoulish are the best perks to include for the Gamma Gun Ghoul build.
Which is the best weapon for a Gamma Gun Ghoul build in Fallout 76?
Gamma Gun is the best weapon for a Gamma Gun Ghoul build in Fallout 76 because it has the capability to deal massive radiation damage in combat.
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