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Maomao returning again to solve medical mysteries with The Apothecary Diaries Season 2 which has 24 episodes in 2025.
The Apothecary Diaries Season 2 is built upon the remarkable success of its debut season in 2023. The series presented us with something refreshingly different: a medical mystery drama set in imperial China.
Maomao, the center of this series, is a brilliant young apothecary within the imperial court’s shadowy halls.
It begins as a lesser-known light novel adaptation into one of 2025’s most awaited anime returns. The first season’s rating on MyAnimeList also speaks about its quality. The expectations soar for what new, interesting journey awaits in the imperial palace.
Let’s break down everything we know about this anticipated second season.
The Apothecary Diaries Season 2 Release Information
For Japanese fans, the series’ first episode will be broadcast on Nippon TV at 11:40 PM JST on 10 January 2025. Also, note that its episodes will be aired every Friday at 11 PM JST.
Other viewers outside of Japan can catch the show on Crunchyroll, which will be streaming the series as it airs. While dub information hasn’t been announced yet, it’s likely to follow given the first season’s successful multilingual release.
Here are the release dates according to different time zones for The Apothecary Diaries Season 2:
| Time Zone | Release Time | Release Day | Release Date |
|---|---|---|---|
| Pacific Standard Time | 7:40 am | Friday | 10 January 2025 |
| Central Standard Time | 9:40 am | Friday | 10 January 2025 |
| Eastern Standard Time | 10:40 am | Friday | 10 January 2025 |
| Greenwich Mean Time | 3:40 pm | Friday | 10 January 2025 |
| Central European Summer Time | 4:40 pm | Friday | 10 January 2025 |
| Indian Standard Time | 9:10 pm | Friday | 10 January 2025 |
| Philippine Time | 11:40 pm | Friday | 10 January 2025 |
| Australia Central Standard Time | 2:10 am | Saturday | 11 January 2025 |
The Apothecary Diaries Season 2 is officially premiering on January 10, 2025. It’s been confirmed that the series will run for 24 episodes across two consecutive cours, giving fans plenty of new mysteries to unravel.
The Apothecary Diaries Season 2 Production Details
The Apothecary Diaries Season 2 brings in some interesting changes to its production team. Akinori Fudesaka is stepping up as the new director, replacing Norihiro Naganuma. Don’t worry, though. Fudesaka worked as assistant director for the first season, suggesting a smooth transition. Naganuma is not leaving entirely; he’s staying on as a head writer to maintain the show’s quality.
The series continues to be a joint production between TOHO Animation Studio and OLM. The creative team includes Yukiko Nakatani handling character designs, Katsumi Takao as art director, and a powerhouse music team comprising Satoru Kousaki, Kevin Penkin, and Alisa Okehazama. The new opening theme, “Hyakka Ryoran,” will be performed by Lilas Ikuta.
The Apothecary Diaries Season 2 Cast
While the core cast of The Apothecary Diaries Season 1 is returning, Season 2 is introducing some new characters. One notable addition is Shisui, voiced by Asami Seto, who shares Maomao’s fascination with unusual subjects – though she prefers bugs to poisons.
The show is also adding an adorable new character that looks like a cat known as the “Admonisher of Thieves” to the inner court.
- Aoi Yuki as Maomao, the sharp-witted apothecary
- Takeo Otsuka as Jinshi, the high-ranking eunuch
- Takuya Kirimoto as Lakan, a talented military tactician
- Katsuyuki Konishi as Gaoshun, Jinshi’s loyal attendant
- Atsumi Tanezaki as Gyokuyo, the most influential precious consort
- Yuko Kaida as Ah-Duo, a pure consort
- Yui Ishikawa as Lihua, a high and wise consort
- Hina Kino as Lishu, a virtuous consort
- Natsumi Kawaida as Fuyou, a middle-rank consort
- Misaki Kuno as Xiaolan, a servant who loves to work with Maomao
What is The Apothecary Diaries Season 2 About
The second season of The Apothecary Diaries promises to deliver more of the intricate medical mysteries and palace intrigue that made the first season such a hit. The latest trailer also reveals new mysterious cases awaiting Maomao’s keen sight, including strange occurrences involving unexplained smells within the court.
Fresh threats involving poison-related incidents suggest that Maomao’s expertise will once again be crucial in protecting the imperial household. These cases appear to be more complex than those in the first season.
Perhaps Season 2 appears to be deepening the relationship between Maomao and Jinshi. The trailer shows a notably warmer interaction between them, with Maomao responding to Jinshi without her usual exasperation.
Does The Apothecary Diaries Have a Manga?
The Apothecary Diaries is based on Natsu Hyuga’s light novel series, which has built a dedicated following. In the US, Square Enix publishes the print version while J-Novel Club handles digital distribution. The anime has been faithfully adapting the source material, giving readers and new viewers plenty to look forward to.
It is shaping up to be one of 2025’s most anticipated anime releases. The series has proven capable of balancing educational elements about ancient Chinese medicine with engaging drama and subtle romance. It does this while maintaining its distinctive atmosphere.
Conclusion
For fans who are wondering if The Apothecary Diaries Season 2 will maintain the quality of the first, all signs point to yes. The production team’s attention to continuity, while bringing a fresh perspective with new staff members, suggests we are in for another interesting journey.
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