What Disease Does Ironmouse Have?

Twitch VTuber Ironmouse has been diagnosed with common variable immunodeficiency (CVID), an immune system disorder.

Ironmouse is one of the most popular VTubers on Twitch (Image via ironmouse/X)

Twitch streamer Ironmouse is a VTuber, i.e., a content creator who uses a unique avatar produced using Computer Graphics (CG) instead of a traditional webcam setup. This avatar also mimics the streamer’s real-life facial expressions and mouth movements through motion capture, providing a more realistic feel to the viewers. VTubers have been making waves in the streaming sphere recently, with creators like Gawr Gura and FILIAN also gaining prominence on Twitch and YouTube.

Ironmouse has common variable immunodeficiency (CVID), a disease associated with the immune system. It leaves the individual with low levels of defensive antibodies and a higher risk of infections. Known for her singing skills, Ironmouse was initially pursuing a career as a coloratura soprano opera singer. However, she had to give it up due to the disease. It leaves her vulnerable to infections in the ears, sinuses, and the respiratory system.

Despite these hardships, Ironmouse has garnered 2.1 million followers on Twitch. Fans can also view her content on her YouTube channel, which holds 1.16 million subscribers. On the other hand, her social media accounts like X and TikTok hold 1 million and 325,000 followers. respectively.


When Ironmouse Overtook Kai Cenat to Become Twitch’s Most Subscribed Creator

On September 30, 2024, Ironmouse reached a new milestone in her content creation career. She became the most subscribed content creator in Twitch history, overtaking Kai Cenat’s previous record of 306,000 concurrent subscribers. The high rise in the subscriber count was due to Ironmouse’s ongoing subathon, which aimed to raise money for the Immune Deficiency Foundation. Half of the subscription money was directly donated by her to the cause. Eventually, she reached an all-time peak of 326,252, setting a new record for the platform.

Soon after her achievement, Kai Cenat congratulated the streamer for breaking his record. Speaking during a “press conference” at his Little Ballers Association (LBA) league event, he said:

“I want to say one thing. First things first, I don’t know if you all know, my sub record got broken today. My world record for streaming? It got broken today. Somebody broke it, somebody took my record. I want to go ahead and congratulate Ironmouse. Clap it up!”

However, he later made certain comments that caused the VTuber’s fanbase to rush in to clarify the process behind bringing a VTuber avatar to life. While defending Ironmouse from online critics during a later broadcast, he mistakenly compared the VTuber to AI, stating:

“I know a lot of people defend me and stuff like that, but chat if you actually looked at her stream and kept up with what she was doing. Not only was it for a good cause, but it was pretty well put together for, you know, AI sh*t.”


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