Here is a complete step-by-step guide to help you complete the Run and Gun Mission in Chapter 4 of Split Fiction.

The Run and Gun Mission is a sub-chapter of Chapter 4: Final Dawn in Split Fiction. This sub-chapter begins when you complete the Test Chambers mission. This mission features obstacles and puzzles like the node puzzle, mechanised robots, lasers, portals, and more.
Here is the detailed guide for the Run and Gun Mission in Chapter 4 of Split Fiction.
Completing the Run and Gun Mission

The Run and Gun Mission in Split Fiction starts with both players standing beneath two different coloured switches. You have to shoot the respective switches to open the door. Inside the door, you will find two vertical green lasers. Disable them by shooting at their source.
To go to the bottom platform, avoid the revolving platform; then, aim at the switches to open a latch below. Continue your journey and climb the wall, where you will spot a gun shooting at you. Destroy the gun, and you will arrive at the node puzzle.
Solving the Node Puzzle

Now, you should put shield busters on the pendulum lever and stand by the switches. Afterwards, shoot at the switches to rotate the lever and open a door. Once you are inside, you will encounter two circular shields. Cross these shields to land in front of purple portals. Navigate via these portals and destroy a gun along the way. This will lead you to two vertical lasers.
Destroy these lasers and drop down into the area where you will face two robot enemies. Defeat them and use the yellow tiles to reach the lift, but be cautious—these tiles disappear after some time. The lift will take you to a toxic river that has some platforms submerged in it. Shoot at the platforms to make them rise, then cross to the other side of the river. Destroy the six lasers ahead of you, and use two oscillating bridges to cross the massive gap. On the other side, you will encounter two more robot enemies that you must defeat.
The Purple Portal Puzzle

Once you defeat the robots, use the purple portals to reach the moving purple portal puzzle. Zoe must move the portal to the right, allowing Mio to cross the green laser. Mio should do the same for Zoe.
Next, climb the ladders while avoiding the lasers, and make your way to the area with two buttons on the ceiling. Shoot these buttons to expose the purple portals and pass through them to the arena for the next boss fight.
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