Painkiller: Best Settings for Radeon RX 7000 Series

These are the optimized settings for playing Painkiller on Radeon RX 7000 series GPUs, which provide an ultra-smooth gaming experience.

Picture of Leper Monk, an elite enemy, in Painkiller
Leper Monk, an elite enemy, in Painkiller (Image via 3D Realms)

Painkiller, the remake of the original game, is built on Unreal Engine 4 instead of UE5. Consequently, there’s no use of advanced features, such as Lumen or Nanite. Therefore, the game is much lighter on the system resources and can run at 60+ FPS on most GPUs, including the Radeon RX 7000 series.

However, if you optimize the settings, Painkiller can run at 120+ FPS without a significant decrease in visual experience. In this article, you will find all the best settings to play Painkiller on the Radeon RX 7000 series cards.

Note: Parts of this article are subjective and reflect the writer’s opinions.

Best Settings To Play Painkiller on Radeon RX 7600 and 7600 XT

Picture of Painkiller video settings page
Painkiller video settings page (Image via 3D Realms)

Playing Painkiller on budget Radeon RX 7600 and 7600 XT GPUs is no problem at all. Both cards can play the game at 1080p with 120+ FPS without any issues for a smooth gaming experience. However, the frame rates are not consistently 120+ in every scene, especially when there are a ton of enemies.

That’s why you must use optimized settings, as they can dramatically boost performance and deliver consistently high frame rates. Here are all the optimized settings:

Note: The settings provided below are based on the game’s recommended specs and shouldn’t be used for resolutions higher than 1920 x 1080.

SettingsRadeon RX 7600Radeon RX 7600 XT
Screen Resolution1920 x 1080 (16:9)1920 x 1080 (16:9)
Resolution Scale100100
Screen ModeBorderlessBorderless
Intel® XeSS Super Resolution 2.0Native Anti-AliasingNative Anti-Aliasing
Sharpness1.51.5
VSyncOff (Turn on if you don’t have a FreeSync or G-Sync monitor)Off (Turn on if you don’t have a FreeSync or G-Sync monitor)
Frame Rate LimitUnlimitedUnlimited
FOV (Field of View)9090
Gamma
Motion BlurOffOff
Graphics QualityCustomCustom
View DistanceFarFar
Anti-AliasingGrayed OutGrayed Out
Post-ProcessingLowLow
Shadows QualityMediumMedium
Texture QualityHighEpic
Effects QualityLowLow
Foliage QualityMediumHigh
Shading QualityHighHigh
Animation QualityHighHigh

Best Settings To Play Painkiller on Radeon RX 7700 XT and 7800 XT

Picture describes Blasting through enemies in Painkiller
Blasting through enemies in Painkiller (Image via 3D Realms)

The Radeon RX 7700 XT and 7800 XT are still two of the best GPUs for budget 1440p gaming, even in 2025. However, the situation is similar to these two cards. To play Painkiller at 1440p with consistent 120+ FPS in every scene, you must use the settings provided below:

Note: The settings provided below are based on the game’s recommended specs and shouldn’t be used for resolutions higher than 2560 x 1440.

SettingsRadeon RX 7700 XTRadeon RX 7800 XT
Screen Resolution2560 x 1440 (16:9)2560 x 1440 (16:9)
Resolution Scale100100
Screen ModeBorderlessBorderless
Intel® XeSS Super Resolution 2.0Native Anti-AliasingNative Anti-Aliasing
Sharpness1.51.5
VSyncOff (Turn on if you don’t have a FreeSync or G-Sync monitor)Off (Turn on if you don’t have a FreeSync or G-Sync monitor)
Frame Rate LimitUnlimitedUnlimited
FOV (Field of View)9090
Gamma
Motion BlurOffOff
Graphics QualityCustomCustom
View DistanceFarFar
Anti-AliasingGrayed OutGrayed Out
Post-ProcessingLowLow
Shadows QualityMediumMedium
Texture QualityHighEpic
Effects QualityLowLow
Foliage QualityMediumHigh
Shading QualityHighEpic
Animation QualityHighHigh

Best Settings To Play Painkiller on Radeon RX 7900 XT and 7900 XTX

Picture describes Painkiller featuring a co-op gameplay
Painkiller features co-op gameplay (Image via 3D Realms)

Gaming at 4K can be quite demanding, and the same is also true for Painkiller. The Radeon RX 7900 XT and 7900 XTX can play Painkiller at 4K but may suffer from frame drops occasionally. If you want to play Painkiller at 4K with 120+ FPS consistently, use the following settings:

Note: The settings provided below are based on the game’s recommended specs and shouldn’t be used for resolutions higher than 3840 x 2160.

SettingsRadeon RX 7900 XTRadeon RX 7900 XTX
Screen Resolution3840 x 2160 (16:9)3840 x 2160 (16:9)
Resolution Scale100100
Screen ModeBorderlessBorderless
Intel® XeSS Super Resolution 2.0QualityQuality
Sharpness1.51.5
VSyncOff (Turn on if you don’t have a FreeSync or G-Sync monitor)Off (Turn on if you don’t have a FreeSync or G-Sync monitor)
Frame Rate LimitUnlimitedUnlimited
FOV (Field of View)9090
Gamma
Motion BlurOffOff
Graphics QualityCustomCustom
View DistanceFarFar
Anti-AliasingGrayed OutGrayed Out
Post-ProcessingLowLow
Shadows QualityMediumMedium
Texture QualityHighEpic
Effects QualityLowLow
Foliage QualityMediumHigh
Shading QualityHighEpic
Animation QualityHighHigh

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