The First Descendant: Best Enzo Build Guide

Discover the Best Enzo Build Guide for The First Descendant and how to create a powerful character with Skills, modules, and weapons.

The First Descendant Best Enzo Build Guide

Creating an effective build in The First Descendant involves carefully selecting and optimizing various components of your character, including modules, reactor stats, weapons, weapon mods, and skills. For an Enzo build, we will focus on optimizing your skill power and survivability. Let us walk you through creating the best Enzo Build in the First Descendant with our guide below.

This guide has been updated for Season 1, Hotfix 1.1.0 of the First Descendant.

Best Enzo Build Guide for The First Descendant

Enzo is a support character in the First Descendant, which increases the ammunition capacity of players in a group. Moreover, he can drop supply drones to fill up everyone’s ammunition, including heavy and special. Enzo is unique and a valuable asset to any team, allowing liberal use of special ammunition for maximal damage.

Unlike other support characters, Enzo has good damage and two explosive drone skills. His survivability is high due to his regenerating shield ability, though he suffers from low mobility. This guide explains how to use Enzo, gear, and modules to help you in the First Descendant.

Enzo Build ProEnzo Build Cons
High SurvivabilityLower Mobility
Group UtilityAverage DPS
Increased Ammo
Best Enzo Build Pros and Cons – The First Descendant Guide

Features and Mechanics for Enzo Build in The First Descendant

The following list presents all the essential Enzo Build Features and Mechanics for the First Descendant:

  • Best Modules: Reinforce Front Line, Skill Cost Optimize, Dual Claw
  • Best Reactor: Materialized Singularity
  • Best Weapons: Enduring Legacy
  • Best Weapon Mods: Rifle Reinforcement, Action and Reaction, Fire Rate Up
  • Best External Component: Tomb Vanguard, Annihilation
  • Descendant Attribute: Non-Attribute
  • Skills
    • Start Supply
    • Explosive Drone
    • Enhance Combat Suit
    • Perfect Support
    • Shoot Support (Passive)
  • Playstyle: supporter
  • How to Unlock: Research for 400,000 or buy for 900 Caliber
  • Story: Executive officer at the command of Albion HQ.

How to unlock Enzo in The First Descendant

How to Unlock Enzo - The First Descendant

To Unlock the Descendant Enzo, craft him with Enzo Enhanced Cells, Enzo Spiral Catalyst, Enzo Code, and 400k credits. Alternatively, you can buy him in the store for 900 caliber. Below is a list of all the parts to craft and research Enzo:

  • 1x Enzo Enhanced Cells
    • 499x Monomolecular Extractor
    • 292x Flectorite
    • 58x Inorganic Biogel
    • 1x Enzo Enhanced Cells Blueprint
    • 200k Gold
  • 1x Enzo Stabilizer
    • 430x Silicon
    • 363x Nanopolymers
    • 90x Advanced Neural Circuit
    • 1x Enzo Stabilizer Blueprint
  • 1x Enzo Spiral Catalyst
    • 290x Semi-permanent Plasma
    • 408x Ceramic Composite
    • 42x Positive Ion Particle
    • 1x Enzo Spiral Catalyst Blueprint
  • 1x Enzo Code
    • Amorphous Material Pattern 025 or 053
  • 400k Credits

Enzo’s Exclusive Equipment

Enzo Exclusive Equipment - Inorganic Matter Spatial Awareness Summons

Rather than exclusive equipment, Enzo has an exclusive Arche ability, the Inorganic Matter Spatial Awareness Summons. You can access it by clicking details in the Descendant menu and customizing the appearance of her suit. Below are the details on Bunny’s Exclusive Equipment:

“Enzo’s Arche ability enables him to summon inorganic matter places in his recognized space to the periphery of his Arche’s range. While it may seem like a near omnipotent ability at first, it has clear limitations. He cannot summon organic matter, and the inorganic matter he can summon consumes his Arche based on their mass, so weapons of a certain level cannot be summoned. However, he virtually can summon an unlimited amount of rounds for tactical squad-use, and for bombing support drones, that are stored in his exclusive armory.”

Best Skill for Enzo

Best Skill for Enzo in the First Descendant

Start Supply is the best skill for Enzo because it gives ammunition to anyone who touches it in combat. With a low cooldown and long duration, Enzo can frequently trigger extra ammunition for himself and other party members, maintaining high DPS with weapons. Moreover, the Transcendent Module Supply Firearm Enhancer makes this skill boost weak point damage and firearm critical hit rate up. Thus, Enzo has a powerful buff to himself and others, making a useful member ofr any party.

The Explosive Drone skill is your AOE and stacks up to two times. You have one defensive skill, Enhanced Combat Suit, that boosts your survivability. Lastly, you want to use your Perfect Support supply ship for mob clear or boss fights. It will use a drone over its duration to attack enemies, provide supply bullets, and fire off a big missile at the end.

Start Supply

Start Supply Skill the FIrst Descendant

Start Supply Features in The First Descendant:

  • Description: Summons a Bullet Supplying Device at the designated location. Supplies bullets to allies that approach the Device. The Bullet Supplying Device can be used once by each ally, and disappears when everyone has used it or its duration ends.
  • Descendant Attribute: Singular
  • Cooldown: 35 seconds
  • MP Cost: 35 Seconds
  • Duration: 12 Seconds
  • Field Supplies: 8%
  • Intercept Battle Supplies: 12%

How to Use Start Supply: this is your main utility skill that you want to use constantly in order to keep ammunition high. As Enzo, you should be using heavy or hard to find ammo and weapons due to this skill. While it does have a long cooldown, the duration is 12 seconds and its not mobile Therefore, place it at a time where you are settling in for a boss fight and mobility isn’t required.

Explosive Drone

Explosive Drone Skill - The FIrst Descendant

Explosive Drone Features in The First Descendant:

  • Description:
  • Descendant Attribute: Dimension
  • Maximum Stacks: 2
  • Stack Cooldown: 22 seconds
  • MP Cost: 20
  • Burst Damage Skill Power x 803.7%
  • Explosive Damage Range: 3 meters
  • Max Expanded Range: 300%
  • Projectile Speed Increase: 0%

How to Use Explosive Drone: you want to use this for AOE damage. The AOE is smaller, so it’s a more single target-focused attack. Moreover, it’s Dimension damage, so if you find it useful to use this to add clarity, select a Dimension reactor for maximum damage.

Enhance Combat Suit

Enhanced Combat Suit Skill - The First Descendant

Enhance Combat Suit Features in The First Descendant:

  • Description: Summons a Shield Recovery Comms. When the Shield Recovery Comms is first summoned, recovers Enzo’s Energy Shield by a certain amount, then continues to recover the Energy Shield through Enhance Combat Suit effect.
  • Descendant Attribute: Dimension
  • Cooldown: 30 seconds
  • MP Cost: 40
  • Duration: 6 seconds
  • Initial Shield Recovery: 20%
  • Continuous Shield Recovery: 4%

How to Use Enhance Combat Suit: this is your way to survive. You want to use this when taking pressure and your shields drop. Be aware, it has a big MP cost, so leave a lot of MP in reserve if you expect to take a heavy load of damage.

Perfect Support

Perfect Support Skill - The First Descendant

Perfect Support Features in The First Descendant:

  • Description: Summons a Small Supply Ship to himself and his allies. The Small Supply Ship periodically provides Supply Bullets and grants Perfect Support to allies. The Small Supply Ship attacks enemies in front while it is active, and when the skill ends, it fires a missile forward that causes a big explosion at its destination.
  • Descendant Attribute: Singular
  • Cooldown: 90 seconds
  • MP Cost: 60
  • Duration: 7.5 Seconds

How to Use Perfect Support: this is your ultimate skill with a huge cooldown You want to save it for boss fights or add clear. The duration is long, so the drone on your shoulder will do tons of damage for you. Moreover, the MP cost is very high, so try to get the resource bricks as you travel around to fill up before a boss burn.

Shoot Support (Passive)

Fire Supporter Skill - The First Descendant

Shoot Support Features in The First Descendant:

  • Description: Grants Fire Support to allies within an area around Enzo, increasing their max ammo capacity. This efficiency of this effect increases marginally with the number of Enzos in the squad. Efficiency increases when Enzo disarms the security of the Encrypted Vault, and rewards increase when this happens.

How to Use Shoot Support: this passive aids in four player content specifically when players are coordinating together. Expect higher ammo and using the drone stock up on heavy and special rounds.

How to play Enzo in The First Descendant

The First Descendant Enzo Character

The best way to play Enzo is by using his ammunition to increase skill Start Supply. This skill feeds you with heavy ammunition, allowing you to consistently fire off Sniper and Grenade Launcher damage. While it has a long cooldown and is not mobile, drop the supply drone in a stationary fight with choke points. Allies can also gain increased ammo, and it’s super helpful for everyone’s DPS.

Enzo’s passive rewards multiplayer with players near him. In instanced-based content, your max ammo will be higher due to this passive. Again, take advantage of the extra ammo and supply drones by constantly using heavy weapons for maximum damage.

For damage, you have an Explosive Drone and Perfect Support. Explosive Drone stacks up to two times and is a smaller 3-meter AOE. However, you can use it back to back to gain a big chunk of burst damage. Perfect Support summons a drone and helps you for about 6 seconds, then fires off a massive missile. You can use both abilities simultaneously for huge damage in a short duration.

When it comes to surviving, use Enzo’s Enhance Combat Suit to quickly recover shields. The MP cost is high with skill, but you’ll dramatically recover shields but won’t be able to heal other allies.

Descendant Modules for Enzo Build

Supply Firearm EnhancerMaximize Duration, and Multitalented are the best modules (mods) for Enzo because they extend his Start Supply and change its usage. The Transcendent Mod changes how Start Supply works, giving you a bonus to weak point damage and a critical hit rate for anyone who touches the Supply drop. Therefore, you build around lowering the cooldown of Start Supply and extending its duration so you and your teammates can gain a buff nearly 100% of the time.

In The First Descendant, modules are essential components that enhance and customize your character’s abilities, stats, and overall performance. Modules can be acquired through questing, missions, loot drops, and vendor items. Moreover, you have limited resources to slot mods; therefore, some slots may be empty depending on your chosen setup.

Enzo Best Modules for Leveling

Enzo Best Modules for Leveling in The First Descendant

Below is a list of the best leveling mods for Enzo Build in the First Descendant:

  • Nimble Fingers – Skill Cooldown -6%
  • Dual Claw – Increases Module Capacity and changes your Sub Attack to a dual claw attack.
  • Front Lines – Skill Critical Hit Damage +16%, Skill Critical Hit Rate +7%.
  • Singular Master – Skill Power +X%, Singular Skill Power Modifier +X%
  • Increased DEF – DEF +16%
  • Increased HP – Max HP 22%
SlotModuleQuality
1 (Skill Module)EmptyN/A
2EmptyN/A
3EmptyN/A
4Nimble FingersStandard
5EmptyN/A
6EmptyN/A
7 (Sub Module)Dual ClawStandard
8EmptyN/A
9Front LinesRare
10Singular MasterRare
11Increased DEFStandard
12Increased HPStandard
Best Leveling Mods for Enzo Build Guide – The First Descendant

Enzo Best Modules

Best Enzo Mods for the First Descendant

Below is a list of the best mods for Enzo Build in the First Descendant:

  • Supply Firearm Enhancer: Summons a firearm enhancement device. Touching the device grants weak point damage and increases the critical hit rate of the firearm.
  • Increased HP: Max HP 22%.
  • Maximize Conservation: Skill cost -9%, skill power modifier -5%.
  • Multitalented: Using a dimension skill reduces cooldowns -5% for 5 seconds.  When using a Fusion skill, skill cost -2%, and duration +2 for 5 seconds.  When using a tech skill, skill range and power modifier +4% for 5 seconds. When using a singular skill, all attribute damage +8 for 5 seconds.
  • MP Conversion: Skill Cooldown -9%, Max MP -4%
  • Nimble Fingers: Skill Cooldown -6%.
  • Long-Distance Maneuvering: Modifies grappling hook range to 25 meters but increases charge time. Also allows more module capacity.
    • Dual Claw remains a good alternative until you find Long-Distance Maneuvering.
  • Stim Accelerant: Max HP +23%, Max MP -4%
  • Skill Extension: Skill duration +9%
  • Increased DEF: DEF +16%
  • Maximize Duration: skill duration +10%, skill power modifier -5%.
  • Flex: put in this position what you feel is lacking, be it survivability, damage, or cooldowns.
SlotModuleQuality
1 (Skill Module)Supply Firearm EnhancerTranscendent
2Increased HPStandard
3Maximize ConservationRare
4MultitalentedUltimate
5MP ConversionRare
6Nimble FingersStandard
7 (Sub Module)Long-Distance ManeuveringUltimate
8Stim AccelerantRare
9Skill ExtensionStandard
10Increased DEFStandard
11Maximize DurationRare
12FlexStandard
Best Mods for Enzo Build Guide – The First Descendant

Best Reactor Stats for Enzo in The First Descendant

Best Reactor Stats for Enzo in The First Descendant

The best reactor for Enzo is Materialized Singularity because it boosts Non-Attribute skills, specifically Start Supply and Perfect Support.  The second option is the Materialized Phase, which boosts non-attribute and Dimension.  This will increase the power of Explosive Drones.  The priority is to buff Non-Attribute skill first, then either Singular or Dimension based on support or damage.  Lastly, make sure to equip the right weapon to activate the bonuses.

In The First Descendant, reactors are powerful enhancements significantly impacting a character’s abilities, stats, and overall performance. Each reactor comes with an “optimal condition,” which requires a specific weapon type to be equipped to activate. Therefore, this should be your primary weapon for the build. They function as core components that provide substantial boosts and unique effects, enabling players to tailor their characters to specific playstyles and strategies.

Weapons for Enzo Build

Enduring Legacy is the best weapon for an Enzo build because the machine gun does incredible damage and debuffs targets, triggering more status effects. Thus, this weapon increases your damage and everyone attacks the boss. Three alternatives are Tamer for bosses, Python for a debuff weapon, or Thunder Cage for mob clear. Your secondary weapon should be Greg’s Reverse Fate for medium range burst damage with bombardment. For range damage, use the Afterglow Sword Sniper Rifle for weak point damage.

The following list presents the best weapon choices for Enzo Build:

  • Enduring Legacy – Machine Gun
  • Greg’s Reversed Fate – Tactical Rifle
  • Afterglow Sword – Sniper Rifle

Enduring Legacy

Enduring Legacy Machine Gun - the First Descendant

Enduring Legacy features in the First Descendant:

  • Firearm ATK: 28
  • Fire Rate: 571
  • Reload Speed: 2.7 seconds
  • Effective Range: 35 meters

The strength of the Enduring Legacy is triggering an extra status effect with the Craftsmanship Perk. Additionally, Enduring Legacy will do more damage than the Tamer, which is a good alternative—another alternative if the Python submachine gun or Thunder Cage.

Greg’s Reversed Fate

Greg’s Reversed Fate Machine Gun- the First Descendant

Greg’s Reversed Fate features in the First Descendant:

  • Firearm ATK: 33
  • Fire Rate: 342
  • Reload Speed: 1.4 seconds
  • Effective Range: 55 meters

The tactical rifle Greg’s Reserved Fate is best for burst AOE damage with Bombardment at medium range. The AOE damage explodes and causes burn damage. Below are the recommended mods for Greg’s Reversed Fate:

  • Fire Rate Up: Fire Rate +6%
  • Better Insight: Firearm Critical Hit Rate +10%
  • Better Concentration: Firearm Critical Hit Damage +8%
  • Concentration Priority: Firearm Critical Hit Damage +8%, Reload Time Modifier -8%
  • Action and Reaction – Firearm ATK +15%, Recoil +5%
  • Rifling Reinforcement – Explosive ATK +12%.
  • Weak Point Sight: Weak point damage +10%, Accuracy -5%
  • Edging Shot: Firearm critical hit rate +11%, firearm ATK -4%
  • Spray and Pray: When landing a firearm critical hit, rounds are not consumed for 3 second (25 second cooldown)

Afterglow Sword

Afterglow Sword Sniper Rifle - the First Descendant

Afterglow Sword features in the First Descendant:

  • Firearm ATK: 240
  • Fire Rate: 66
  • Reload Speed: 2.5 seconds
  • Effective Range: 55 meters
  • Nightmare Reaper: on hitting an enemy’s weak point, inflicts the unique ability death propagation. On hitting an enemy commander or collossi, increase firearm critical hit rate and apply the effect to the attack.

The Afterglow Sword Sniper Rifle is the best choice for ranged precision weak point damage. Once you trigger Death Propagation, you gain increased reload and damage on weak points. Use this weapon for ranged headshots if possible. Below are the recommended mods for the Afterglow Sword Sniper Rifle:

  • Special Sight – Movement Speed when Aiming -8%, Weak Point DMG when Aiming +8%
  • Action and Reaction – Firearm ATK +15%, Recoil +5%
  • Rifling Reinforcement – Explosive ATK +12%
  • Better Insight – Firearm Critical Hit Rate +10%
  • Edging Shot – Firearm Critical Hit Rate +8%, Firearm ATK -4%
  • Better Concentration – Firearm Critical Hit Damage +19%
  • Concentration Priority – Firearm Critical Hit Damage +30%, Reload Time Modifier -8%
  • Fire Rate Concentration – Fire Rate +8%, Firearm Critical Hit Damage +6.5%
  • Focus Fire – Weak Point Damage +8%, Firearm Critical Hit Damage +6.5%
  • Weak Point Sight – Weak Point Damage +9%

External Component

The First Descendant External Component Tomb Vanguard Set Traits
The First Descendant External Component Annihilation Set Traits

The Tome Vanguard and the Annihilation set are the best external components for Enzo. The two-piece Tomb Vanguard gives 25% DEF, making you incredibly durable, while Annihilation increases Skill Duration. Alternatively, you can run four-piece Annihilation or Bravery sets. Regarding stats, prioritize Max HP, DEF, and elemental resistance like Toxic, Chill, Fire, or Electric Resistance. Below are the best External Component bonuses to prioritize for the Enzo Build guide in the First Descendant:

First Bonus:

  1. HP
  2. DEF
  3. Shields

Second Bonus

  1. Max Resource (HP, MP, DEF, Shields)
  2. Elemental resistance (fire, chill, electric, toxic)
Auxiliary PowerSensorMemoryProcessor
First Bonus PriorityFirst Bonus PriorityFirst Bonus PriorityFirst Bonus Priority
HP
DEF
Shields
HP
DEF
Shields
HP
DEF
Shields
HP
DEF
Shields
Second Bonus Priority Second Bonus Priority Second Bonus Priority Second Bonus Priority
Max HP
Fire Resistance
Max MP
Chill Resistance
DEF
Electric Resistance
Max Shields
Toxin Resistance
Best External Component Stats – Enzo Build Guide

Recent Updates and Changes for Enzo Build

All Season 1 Invasion Cosmetics for The First Descendant

The biggest change and update to Enzo during Season One is the addition of Invasions and Inversion Reinforcement. Enzo can hold his own in the new Invasion content, but lacks the speed to be a great choice. Players are rewarded for completion time and materials used for the newest Descendant Hailey. Inversions should be done often to work toward unlocking new gear and the newest Descendent.

Enzo Story in the First Descendant

If asked to pick the most important factors for winning a war, the general response would be powerful weapons, a strong fighting force, and cutting-edge technology. However, Enzo would beg to differ.

Powerful weapons must be transported to the front lines on time, and a strong fighting force must be well-fed and capable of shooting accurately. Also, cutting-edge technology demands sufficient resources to sustain mass production. As such, for Enzo, the most important factor in winning a war is a seamless and systematic supply flow. If only such things had been achievable at that time… Enzo continues to blame himself for what had happened to his cousin, Lepic, as well as the annihilation of the 44th Grenadier Squad.

In the past, during the Agna Desert Defense Operation, Enzo, who had been quartermaster at the time, drove towards the front lines in a tactical armored vehicle to deliver the much needed ammunition to the besieged 44th Grenadier Squad
Not only did he intend to rescue his sole surviving blood relative, Lepic, but it was a race against the clock, as the timely supply of ammunition could turn the tide of battle.

But perhaps he was too hasty. The Supply Squad, which was enroute without a proper escort, was ambushed by the Vulgus, and all of the ammunition they were carrying was lost in the ensuing explosion. Now, it was he, not the 44th Grenadier Squad, who was in danger of losing his life. Despite finding himself facing death, he instead despaired at the fact that he had lost the ammunition which he needed to deliver to his teammates. That feeling of hopelessness… Losing both his comrades and his cousin this way…

Enzo’s Story Continued

At that moment, supplies started to appear from the ground on where he had been crying out in despair. It was later revealed that this phenomenon had been caused by Enzo’s Arche ability, Inorganic Matter Spatial Awareness Summoning, and this ammunition had been summoned from a faraway Albion ammunition depot. However, Enzo, who was unaware of this fact, believed that a miracle had happened and defeated the enemies by himself, eventually succeeding in transporting the supplies to the 44th Grenadier Squad’s location.

But there would be no second miracle. By the time he arrived, the Grenadier Squad had been wiped out, and Lepic, who was lucky enough to survive, had lost his right arm. Although Lepic would overcome adversity and become an outstanding Descendant, Enzo blamed himself, believing that if there had been no issues with the supply flow, a loss of this scale could have been prevented in the first place.

Never again would he allow himself to fail. Through perfect supply operations, he would save his comrades and win the war. Even now, as a Descendant under the direct command of Albion HQ, and as an executive officer, he is always revisiting the events of that day, repeating his promise. And whenever there is place that requires assistance, he will go in person to the front, providing as many supplies as the soldiers needed. His aim? To make something as essential for victory as supplies be considered a given and not a miracle.

Best Enzo Build Guide Summary – The First Descendant

  • Reactor: Materialized Singularity
  • Weapons
    • Enduring Legacy – Machine Gun
    • Greg’s Reversed Fate – Tactical Rifle
    • Afterglow Sword – Sniper Rifle
  • Weapon Mods
    • Rifling Reinforcement 
    • Fire Rate Up
    • Action and Reaction
  • External Component Set
    • 2x Annihilation
    • 2x Vanguard
  • Skills
    • Start Supply
    • Explosive Drone
    • Enhance Combat Suit
    • Perfect Support
    • Shoot Support (Passive)

Best Mods

  • Supply Firearm Enhancer
  • Increased HP
  • Maximize Conservation
  • Multitalented
  • MP Conversion
  • Nimble Fingers
  • Long-Distance Maneuvering
  • Stim Accelerant
  • Skill Extension
  • Increased DEF
  • Maximize Duration

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